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SML1924

T1AM

≥98% (HPLC), neuromodulator , powder

Synonym(s):

3-Iodothyronamine hydrochloride, 4-[4-(2-Aminoethyl)-2-?iodophenoxy]phenol hydrochloride (1:1)

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About This Item

Empirical Formula (Hill Notation):
C14H14INO2 · HCl
CAS Number:
788824-64-6
Molecular Weight:
391.63
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
MFCD11973725
Assay:
≥98% (HPLC)
Form:
powder
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Product Name

T1AM, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 10 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC1=CC=C(OC2=C(I)C=C(CCN)C=C2)C=C1.[H]Cl

InChI

1S/C14H14INO2.ClH/c15-13-9-10(7-8-16)1-6-14(13)18-12-4-2-11(17)3-5-12;/h1-6,9,17H,7-8,16H2;1H

InChI key

RVKVVMXTPQCCIX-UHFFFAOYSA-N

Biochem/physiol Actions

3-iodothyronamine (T1AM) is present in vertebrate tissues and the circulatory system. Its physiological effects are the opposite of the thyroid hormone. T1AM acts as a neuromodulator as well as a hormone-like molecule.
T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone.
T1AM (3-Iodothyronamine) is an endogenous biogenic amine derived from thyroid hormone. T1AM is a potent agonist of trace amine-associated receptor TAAR1 (TAR1, TA1), a GPCR primarily found in the brain.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

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