SML1966
SK609 hydrochloride
≥98% (HPLC)
别名:
4-(2-Chlorophenyl)butan-2-amine hydrochloride, ES609, SK609•HCl
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light, under inert gas
assay
≥98% (HPLC)
form
powder
storage condition
protect from light, under inert gas
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
Dopamine D3 receptor (D3R) selective agonist
SK609 (ES609) is a Dopamine D3 receptor (D3R) selective agonist with a bias towards the G-protein-dependent pathway rather than recruiting β-arrestin-2 and an EC50 value of 113.9 nM for activation of ERK1/2 phosphorylation. SK609 has been shown to reverse akinesia and reduce L-dopa-induced dyskinesia in a hemiparkinsonian rat model of Parkinson′s desease. It does not induce desensitization of D3R.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable