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About This Item
Empirical Formula (Hill Notation):
C25H19ClN2O5S
CAS Number:
Molecular Weight:
494.95
UNSPSC Code:
12352200
NACRES:
NA.77
Assay
≥98% (HPLC)
color
white to beige
solubility
DMSO: 2 mg/mL, clear
shipped in
ambient
storage temp.
2-8°C
SMILES string
O=C1C(O)=C(C(OCC)=O)C(C2=CC=C(C3=CC=C(Cl)C=C3)O2)N1C4=NC(C=CC(C)=C5)=C5S4
Biochem/physiol Actions
Allosteric inhibitor of atypical PKC isoforms
PS432 is an allosteric inhibitor of Protein Kinase C (PKC) that targets regulatory site (PIF-pocket) present in the kinase domain. PS432 potently inhibits non-small cell lung cancer cells proliferation and tumor growth without side effects in a mouse xenograft model.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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