SML2023
UCSF924NC
≥98% (HPLC)
Synonym(s):
6-Methyl-2-((3-(pyridin-4-yl)propylamino)methyl)quinolin-4(1H)-one
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About This Item
Empirical Formula (Hill Notation):
C19H21N3O
CAS Number:
Molecular Weight:
307.39
UNSPSC Code:
51111800
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
CC1=CC2=C(NC(CNCCCC3=CC=NC=C3)=CC2=O)C=C1
Biochem/physiol Actions
Negative control for the dopamine D4 receptor (DRD4) partial agonist UCSF924.
UCSF924NC (Compound 9-6-16; ZINC000091707446) is the recommended negative control compound for the high-affinity dopamine D4 receptor (DRD4) partial agonist UCSF924 (Compound 9-6-24; ZINC000091726127). UCSF924NC exhibits a 1/2500-fold reduced D4 affinity when compared with that of UCSF924.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Sheng Wang et al.
Science (New York, N.Y.), 358(6361), 381-386 (2017-10-21)
Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded. To illuminate dopamine receptor structure, function, and
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML2023-5MG | 04061835249770 |
| SML2023-25MG | 04061835249763 |