SML2053
Lalistat 2
≥98% (HPLC), lysosomal acid lipase (LAL) inhibitor, powder
Synonym(s):
1-Piperidinecarboxylic acid 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester, Lalistat-2
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About This Item
Empirical Formula (Hill Notation):
C13H20N4O2S
CAS Number:
Molecular Weight:
296.39
UNSPSC Code:
41106300
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Product Name
Lalistat 2, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(N1CCCCC1)OC2=NSN=C2N3CCCCC3
InChI key
PNYYVHOTXOEBEV-UHFFFAOYSA-N
Application
Lalistat 2 has been used as a lysosomal acid lipase (LAL) inhibitor to study its effects on hypoxia-inducible factor (HIF) in mice. It has also been used as a LAL inhibitor to study LAL activity on dried blood spot cards.
Biochem/physiol Actions
Lalistat-2 is a potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa). Lalistat-2 affects lipid droplets morphology and localization.
potent and specific competitive inhibitor of the lysosomal acid lipase (LAL/Lipa).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
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