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SML2054

SEA0400

≥98% (HPLC), Na+−Ca++ exchanger (NCX) inhibitor, powder

Synonym(s):

SEA0400, 2-[4-[(2,5-Difluorophenyl)methoxy]phenoxy]-5-ethoxybenzenamine, SEA 0400

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About This Item

Empirical Formula (Hill Notation):
C21H19F2NO3
CAS Number:
223104-29-8
Molecular Weight:
371.38
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
MFCD07772188
Assay:
≥98% (HPLC)
Form:
powder
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Product Name

SEA0400, ≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

color

white to beige

shipped in

ambient

storage temp.

−20°C

SMILES string

CCOC1=CC=C(OC2=CC=C(OCC3=C(F)C=CC(F)=C3)C=C2)C(N)=C1

InChI

1S/C21H19F2NO3/c1-2-25-18-8-10-21(20(24)12-18)27-17-6-4-16(5-7-17)26-13-14-11-15(22)3-9-19(14)23/h3-12H,2,13,24H2,1H3

InChI key

YSUBLPUJDOWYDP-UHFFFAOYSA-N

Biochem/physiol Actions

Potent and selective inhibitor of Na+−Ca++ exchanger (NCX)
SEA0400 is a potent and selective inhibitor of Na+/Ca2+exchanger (NCX). SEA0400 potently inhibits Na+/Ca2+ exchanger activity in rat astrocytes, microglia, cultured neurons, and rat cardiomyocytes.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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