SML2058
5,7-Dihydroxytryptamine hydrobromide
≥94% (HPLC)
Synonym(s):
3-(2-Aminoethyl)-1H-indole-5,7-diol, 5,7-DHT hydrobromide, 5,7-DiHT hydrobromide, 7-Hydroxyserotonin hydrobromide
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About This Item
Empirical Formula (Hill Notation):
C10H12N2O2 · xHBr
CAS Number:
Molecular Weight:
192.21 (free base basis)
UNSPSC Code:
12352116
NACRES:
NA.77
MDL number:
Product Name
5,7-Dihydroxytryptamine hydrobromide, ≥94% (HPLC)
InChI
1S/C10H12N2O2/c11-2-1-6-5-12-10-8(6)3-7(13)4-9(10)14/h3-5,12-14H,1-2,11H2
SMILES string
NCCC1=CNC2=C(O)C=C(O)C=C21.[H]Br
InChI key
LXWHQTNFZDTKBH-UHFFFAOYSA-N
assay
≥94% (HPLC)
form
powder
storage condition
desiccated
color
white to dark brown
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
5,7-Dihydroxytryptamine is a neurotoxin that selectively kills serotonergic neurons.
Neurotoxin that selectively kills serotonergic neurons.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Manfred Göthert
Pharmacological reports : PR, 65(4), 771-786 (2013-10-23)
This review contains background information on the serotonin system, furthermore the suggestion to introduce the term Contemporary Witness Report (CWR) for a novel type of review and, as the main part, an overview over the history of serotonin discovery as
Pavel M Balaban et al.
Scientific reports, 6, 36933-36933 (2016-11-15)
We analyzed changes in the activity of individually identifiable neurons involved in the networks underlying feeding and withdrawal behaviors in snails before, during, and after aversive learning in vitro. Responses to food in the "reinforcing" serotonergic neurons involved in withdrawal
Rani K Vasudeva et al.
Behavioural brain research, 295, 35-44 (2015-06-16)
Alcoholism afflicts 1 in 13 US adults, and comorbidity with depression is common. Levels of serotonin (5-HT) metabolites in alcoholic or depressed humans and rat strains are lower compared to healthy counterparts. Rats bred for ethanol (EtOH) preference are common
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