SML2087
SJ000291942
≥98% (HPLC)
Synonym(s):
2-(4-Ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)-acetamide
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About This Item
Empirical Formula (Hill Notation):
C16H15FN2O4
CAS Number:
Molecular Weight:
318.30
UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:
InChI
1S/C16H15FN2O4/c1-2-11-3-6-13(7-4-11)23-10-16(20)18-12-5-8-14(17)15(9-12)19(21)22/h3-9H,2,10H2,1H3,(H,18,20)
InChI key
YSZJLXPXVFGTNK-UHFFFAOYSA-N
SMILES string
CCC1=CC=C(OCC(NC2=CC([N+]([O-])=O)=C(F)C=C2)=O)C=C1
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
Activator of Bone Morphogenetic Protein (BMP) signaling
SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value < 1 μM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilage, but are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryos, activate SMAD1/5/8 phosphorylation, and induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation.
Storage Class
11 - Combustible Solids
wgk
WGK 3
Regulatory Information
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