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SML2088

Sigma-Aldrich

Procainamide hydrochloride

≥98% (HPLC), powder, sodium channel blocker

Synonym(s):

Procainamide hydrochloride, 4-Amino-N-(2-diethylaminoethyl)benzamide hydrochloride, 4-Aminobenzoic acid 2-diethylaminoethylamide, Amidoprocaine, Amisalin, Cardiorytmin, HC 5006, Novocaine amide hydrochloride, Novocamid hydrochloride, Procainamide monohydrochloride, Procamid, Procamide, Procan SR, Procapan, Procardyl, Pronestyl, Pronestyl hydrochloride, Spicain amide

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20 μG
¥2,253.83
50 μG
¥4,055.60

About This Item

Linear Formula:
H2NC6H4CONHCH2CH2N(C2H5)2·HCl
CAS Number:
614-39-1
Molecular Weight:
271.79
Beilstein:
3729517
EC Number:
210-381-7
MDL number:
MFCD00012998
UNSPSC Code:
12352200
NACRES:
NA.77

¥2,253.83

Estimated to ship on2025年12月08日Details

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Product Name

Procainamide hydrochloride, ≥98% (HPLC)

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

mp

167-169 °C (lit.)

solubility

H2O: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

Cl.CCN(CC)CCNC(=O)c1ccc(N)cc1

InChI

1S/C13H21N3O.ClH/c1-3-16(4-2)10-9-15-13(17)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3,(H,15,17);1H

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This Item
483311467839401587
铝酸铋 水合物 ≥99.9%

Sigma-Aldrich

510289

铝酸铋 水合物

磷酸铋(III) 99.99%

Sigma-Aldrich

483311

磷酸铋(III)

硝酸铋(III) 五水合物 ≥99.99% trace metals basis

Sigma-Aldrich

467839

硝酸铋(III) 五水合物

醋酸铋 (III) ≥99.99% trace metals basis

Sigma-Aldrich

401587

醋酸铋 (III)

reaction suitability

core: bismuth, reagent type: catalyst

reaction suitability

core: bismuth, reagent type: catalyst

reaction suitability

core: bismuth, reagent type: catalyst

reaction suitability

core: bismuth, reagent type: catalyst

assay

≥99.9%

assay

99.99%

assay

≥99.99% trace metals basis

assay

≥99.99% trace metals basis

Application

Procainamide hydrochloride (PAH) is suitable to investigate its binding behavior with human serum albumin[1] and bovine serum albumin[2] by fluorescence quenching study to understand the pharmacokinetic and pharmacodynamic mechanisms of PAH.[2][1]

Biochem/physiol Actions

Procainamide hydrochloride is a sodium channel blocker and Class IA anti-arrhythmic. It has also been shown to Inhibit DNA methyltransferase and modulate epigenetic regulation of gene expression.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H315,H319,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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    Certificates of Analysis (COA)

    Lot/Batch Number
    0000496200
    0000496199
    0000496199
    0000496200
    0000434900

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    Investigation of the interaction of the new antiarrhythmic drug procainamide hydrochloride with bovine serum albumin and the effect of some metal ions on the binding: a fluorescence quenching study
    Meti MD, et al.
    Monatshefte fur Chemie / Chemical Monthly, 144(8), 1253-1259 (2013)
    Kirthi Byadagi et al.
    Journal of pharmaceutical analysis, 7(2), 103-109 (2018-02-07)
    Interaction of procainamide hydrochloride (PAH) with human serum albumin (HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms of the drug. Multi-spectroscopic techniques were used to investigate the binding mode of PAH to HSA and results revealed

    Articles

    Released N-Glycan Analysis of a Therapeutic Antibody Using BIOshell™ Glycan Column

    This application note describes the released N-Glycan analysis of a monoclonal antibody, cetuximab, labeled with procainamide, using a BIOshell™ Glycan HPLC column.

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