SML2090
NAMI-A
≥98% ruthenium (Ru) basis (elemental analysis)
Synonym(s):
1H-Imidazole (OC-6-11)-tetrachloro(1H-imidazole-κN3)[1,1′-(sulfinyl-κS)bis[methane]]ruthenate(1-) (1:1), ImH[trans-RuCl4(DMSO)Im], Imidazolium trans-imidazoledimethyl sulfoxide-tetrachlororuthenate
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About This Item
Empirical Formula (Hill Notation):
C5H10Cl4N2ORuS · C3H5N2
CAS Number:
Molecular Weight:
458.18
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% ruthenium (Ru) basis (elemental analysis)
Form:
powder
Storage condition:
desiccated
assay
≥98% ruthenium (Ru) basis (elemental analysis)
form
powder
storage condition
desiccated
color
faint red to dark brown
solubility
H2O: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
CS(C)=O.Cl[Ru](Cl)(Cl)Cl.N1=CNC=C1.C2=[NH+]C=CN2
InChI key
HIAWXYSWERGOAJ-UHFFFAOYSA-K
Biochem/physiol Actions
NAMI-A is a ruthenium-based anticancer agent.
NAMI-A is a potent antimetastatic drug in vivo that is exhibits little cytotoxicity towards many cancer cell lines. Antimetastatic of NAMI-A is attributed to the formation of adducts with membrane and cytosolic proteins. Nevertheless NAMI-A induces potent and selective cytotoxic effects in several leukemia cell lines. NAMI-A exhibits low toxicity for host tissues.
potent antimetastatic drug
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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