Key Documents

View All Documentation

SML2132

Brazilin

Name: Brazilin
Brand: SIGMA

anti-inflammatory agent

Synonym(s):

Brasilin, (+)-Brazilin, (6aS,11bR)-7,11b-Dihydro-benz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol, 7, 11b-dihydrobenz[b]indeno[1,2-d]pyran-3,6a,9,10 (6H)-tetrol, NSC 56652, 6,6a,7,11b-Tetrahydro-3,6a,9,10-tetrahydroxyindeno[2,1-c]chromene, Natural Red 24

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₄O₅

CAS Number:

474-07-7

Molecular Weight:

286.28

NACRES:

NA.77

UNSPSC Code:

12352200

EC Number:

207-477-6

MDL number:

MFCD00210817

Colour Index Number:

75280

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Product Name

Brazilin,

optical activity

[α]/D 108.0 to 133.0°, c = 0.5 in methanol

color

white to very dark brown

solubility

DMSO: 2 mg/mL

storage temp.

2-8°C

SMILES string

O1C[C@]2([C@@H](c4c1cc(cc4)O)c3c(cc(c(c3)O)O)C2)O

InChI

1S/C16H14O5/c17-9-1-2-10-14(4-9)21-7-16(20)6-8-3-12(18)13(19)5-11(8)15(10)16/h1-5,15,17-20H,6-7H2/t15-,16+/m0/s1

InChI key

UWHUTZOCTZJUKC-JKSUJKDBSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Bioactive Small Molecules

Biochem/physiol Actions

Brazilin is a natural isoflavonoid red pigment with many biologic activities including neuroprotective, anti-inflammatory, antibacterial, antiproliferative, and antioxidant properties. Some of its activity is thought to be due to its regulation of the transcription factor NF-ΚB.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Brazilin exerts protective effects against renal ischemia-reperfusion injury by inhibiting the NF-κB signaling pathway.

Yanyan Jia et al.

International journal of molecular medicine, 38(1), 210-216 (2016-06-02)

Renal ischemia-reperfusion (I/R) injury is associated with high morbidity and mortality as there is currently no available effective therapeutic strategy with which to treat this injury. Thus, the aim of this study was to investigate the potential protective effects of

Brazilin Ameliorates Diabetic Nephropathy and Inflammation in db/db Mice.

Zhan-Yuan Li et al.

Inflammation, 40(4), 1365-1374 (2017-05-13)

Hyperglycemia and inflammation play important roles in the pathogenesis of diabetic nephropathy (DN). Brazilin might be an effective pharmacological agent against hyperglycemia and inflammation. In our present study, we explored whether brazilin mitigated pathological progression, inflammation, and extracellular matrix (ECM)

Lifespan-extending and stress resistance properties of brazilin from Caesalpinia sappan in Caenorhabditis elegans.

Eun Byeol Lee et al.

Archives of pharmacal research, 40(7), 825-835 (2017-07-02)

This study contributes to the continual discovery of lifespan-extending compounds from plants, using the Caenorhabditis elegans model system. An ethyl acetate soluble fraction of methanol extract from the heartwood of Caesalpinia sappan showed a significant lifespan-extending activity. Subsequent activity-guided chromatography

Global Trade Item Number

SKU	GTIN
SML2132-25MG	04061835360260
SML2132-5MG	04061835360284

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service