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Merck
CN

SML2150

AZ6102

≥98% (HPLC)

Synonym(s):

rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one

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About This Item

Empirical Formula (Hill Notation):
C25H28N6O
CAS Number:
Molecular Weight:
428.53
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light
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assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

CN1C=CC2=C1N=C(C3=CC=C(C4=CN=C(N5C[C@H](C)N[C@H](C)C5)C=C4C)C=C3)NC2=O

Biochem/physiol Actions

AZ6102 is a potent and selective Tankyrase 1/2 (TAMKS1/2) inhibitor that has 100-fold selectivity against other PARP family enzymes. AZ6102 is moderately orally bioavailable in rat and mice.
bioavailable, potent and selective Tankyrase 1/2 (TAMKS1/2) inhibitor


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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