SML2190
BRD5529
≥98% (HPLC)
别名:
2-[4′-(Aminocarbonyl)[1,4′-bipiperidin]-1′-yl]-5-[(4-methylbenzoyl)amino]-3-pyridinecarboxylic acid
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
CC1=CC=C(C(NC2=CC(C(O)=O)=C(N3CCC(N4CCCCC4)(C(N)=O)CC3)N=C2)=O)C=C1
InChI
1S/C25H31N5O4/c1-17-5-7-18(8-6-17)22(31)28-19-15-20(23(32)33)21(27-16-19)29-13-9-25(10-14-29,24(26)34)30-11-3-2-4-12-30/h5-8,15-16H,2-4,9-14H2,1H3,(H2,26,34)(H,28,31)(H,32,33)
InChI key
ZXWHESBABUHJBE-UHFFFAOYSA-N
Biochem/physiol Actions
BRD5529 is a cell penetrant inhibitor of CARD9-TRIM62 interaction that binds to wt CARD9, preventing TRIM62 binding and ensuing inflammation. BRD5529 binding to CARD9 results in decrease ubiquitination.
Cell penetrant inhibitor of CARD9-TRIM62 interaction
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable