SML2291
S119-8
≥98% (HPLC)
Synonym(s):
4-(tert-butyl)-N-(4-(phenylamino)phenyl)benzamide, Benzamide, 4-(1,1-dimethylethyl)-N-[4-(phenylamino)phenyl]
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About This Item
Empirical Formula (Hill Notation):
C23H24N2O
CAS Number:
Molecular Weight:
344.45
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
InChI key
NEPKMQDGCTXOPG-UHFFFAOYSA-N
SMILES string
O=C(C1=CC=C(C(C)(C)C)C=C1)NC2=CC=C(NC3=CC=CC=C3)C=C2
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Related Categories
Biochem/physiol Actions
Inhibitor of viral nucleoprotein of influenza A and B
S119-8 is an inhibitor of viral nucleoprotein of influenza A and B. It showed synergistic effects with oseltamivir.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Kris M White et al.
ACS infectious diseases, 4(2), 146-157 (2017-12-23)
S119 was a top hit from an ultrahigh throughput screen performed to identify novel inhibitors of influenza virus replication. It showed a potent antiviral effect (50% inhibitory concentration, IC50 = 20 nM) and no detectable cytotoxicity (50% cytotoxic concentration, CC50
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