SML2299
Photoregulin3
≥98% (HPLC)
Synonym(s):
2-[(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-6,7-dimethoxy-4(3H)-quinazolinone, PR3
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About This Item
Empirical Formula (Hill Notation):
C22H23N3O3
CAS Number:
Molecular Weight:
377.44
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
OC(C1=C2)=NC(CN3CCC(C4=CC=CC=C4)=CC3)=NC1=CC(OC)=C2OC
InChI
1S/C22H23N3O3/c1-27-19-12-17-18(13-20(19)28-2)23-21(24-22(17)26)14-25-10-8-16(9-11-25)15-6-4-3-5-7-15/h3-8,12-13H,9-11,14H2,1-2H3,(H,23,24,26)
InChI key
CKCSOMMBIPJYSG-UHFFFAOYSA-N
Biochem/physiol Actions
Nr2e3 modulator
Photoregulin3 is a modulator of the rod transcription factor Nr2e3 that inhibits rod photoreceptor gene expression. Photoregulin3 significantly rescues photoreceptor in RhoP23H mice.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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