SML2309
Oxaphenamide
≥98% (HPLC)
Synonym(s):
2-Hydroxy-N-(4-hydroxyphenyl)benzamide, 4′-Hydroxysalicylanilide, Osalmide, Oxaphenamide, p-hydroxyphenylsalicylamide
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About This Item
Empirical Formula (Hill Notation):
C13H11NO3
CAS Number:
Molecular Weight:
229.23
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
208-385-9
MDL number:
SMILES string
N(c2ccc(cc2)O)C(=O)c1c(cccc1)O
InChI key
LGCMKPRGGJRYGM-UHFFFAOYSA-N
InChI
1S/C13H11NO3/c15-10-7-5-9(6-8-10)14-13(17)11-3-1-2-4-12(11)16/h1-8,15-16H,(H,14,17)
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Related Categories
Biochem/physiol Actions
Osalmid is a potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid inhibits RR (ribonucleotide reductase) activity in vivo, and exhibits synergistic effect with lamivudine on inactivation mutant HBV strain. Osalmid is a biliation activator (choleretic agent), but a mechanism of this activity remains unknown.
potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis; choleretic agent
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
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