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Merck
CN

SML2341

Nω-Propyl-L-Arginine hydrochloride

≥98% (HPLC)

Synonym(s):

L-NPA, N(ω)-Propyl-L-arginine, N(w)-Propyl-L-arginine, N-ω-Propyl-L-arginine, N-Omega-propyl-L-Arginine, N5-[Imino(propylamino)methyl]-L-ornithine, NG-Propyl-L-arginine, NPA, NPLA, Nomega-Propyl-L-Arginine, PLA, p-ARG

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About This Item

Empirical Formula (Hill Notation):
C9H20N4O2 · xHCl
CAS Number:
Molecular Weight:
216.28 (free base basis)
UNSPSC Code:
12352209
MDL number:
Assay:
≥98% (HPLC)
Form:
film
Storage condition:
desiccated
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assay

≥98% (HPLC)

form

film

storage condition

desiccated

color

colorless

solubility

H2O: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CCCNC(NCCC[C@H](N)C(O)=O)=N

InChI

1S/C9H20N4O2/c1-2-5-12-9(11)13-6-3-4-7(10)8(14)15/h7H,2-6,10H2,1H3,(H,14,15)(H3,11,12,13)/t7-/m0/s1

InChI key

AOMXURITGZJPKB-ZETCQYMHSA-N

Biochem/physiol Actions

Nω-Propyl-L-arginine (NPA; NPLA; p-ARG; L-PNA) is a substrate-competitive, reversible, potent and selective neuronal nitric oxide synthase (nNOS; bNOS) inhibitor (Ki = 57 nM/bovine nNOS, 8.5 μM/bovine eNOS, 180 μM/murine iNOS) widely used for probing nNOS-dependent physiological and pathological processes both in cultures and in animals in vivo.
Substrate-competitive, reversible, potent and selective neuronal nitric oxide synthase (nNOS; bNOS) inhibitor with in vitro and in vivo efficacy.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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