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Merck
CN

SML2365

Phenprocoumon

≥97% (HPLC)

Synonym(s):

2-Hydroxy-3-(1-phenylpropyl)-4H-1-benzopyran-4-one, 4-Hydroxy-3-(1-phenylpropyl)-2H-1-Benzopyran-2-one

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About This Item

Empirical Formula (Hill Notation):
C18H16O3
CAS Number:
Molecular Weight:
280.32
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
Assay:
≥97% (HPLC)
Form:
powder
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assay

≥97% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C18H16O3/c1-2-13(12-8-4-3-5-9-12)16-17(19)14-10-6-7-11-15(14)21-18(16)20/h3-11,13,20H,2H2,1H3

InChI key

QNDUUBVQYBBRBW-UHFFFAOYSA-N

Biochem/physiol Actions

Coumarin derivative that inhibits vitamin K and acts as a long acting oral anticoagulant
Phenprocoumon is a coumarin derivative that inhibits vitamin K and acts as a long acting oral anticoagulant. It was recently found to act synergistically with flutamide to modulate the stability of the androgen receptor (AR) and resensitize AR-mutant prostate cancer cells to flutamide.


pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Repr. 2 - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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