SML2386
Cycloguanil hydrochloride
≥95% (HPLC)
Synonym(s):
1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine hydrochloride
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C11H14ClN5 · HCl
CAS Number:
Molecular Weight:
288.18
UNSPSC Code:
12352200
MDL number:
NACRES:
NA.21
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
Clc1ccc(cc1)N2C(NC(=N)NC2=N)(C)C.Cl
InChI
1S/C11H14ClN5.ClH/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8;/h3-6H,1-2H3,(H4,13,14,15,16);1H
InChI key
MOUAPRKJJUXEIE-UHFFFAOYSA-N
Application
Cycloguanil hydrochloride is suitable for use as a positive control in screening Plasmodium falciparum strains in microdilution radioisotope antiplasmodial bioassay. It may also be used as internal standard in high performance liquid chromatography for the quantification of urine and plasma samples.
Biochem/physiol Actions
Cycloguanil is it a potential antimalarial drug. It is hydrophilic in nature. Cycloguanil acts as a substrate for the enzyme organic cation transporter 1 (OCT1).
Cycloguanil, a metabolite of proguanil, is a potent dihydrofolate reductase inhibitor.
Dihydrofolate reductase inhibitor, metabolite of proguanil
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.