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SML2388

SW157765

≥98% (HPLC)

Synonym(s):

3-(2-Furanyl)-N-[2-(4-pyridinyl)-5-benzoxazolyl]-2-propenamide

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About This Item

Empirical Formula (Hill Notation):
C19H13N3O3
CAS Number:
332063-87-3
Molecular Weight:
331.32
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD01539854
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to brown

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N(c2cc3nc([o]c3cc2)c4ccncc4)C(=O)\C=C\c1[o]ccc1

InChI

1S/C19H13N3O3/c23-18(6-4-15-2-1-11-24-15)21-14-3-5-17-16(12-14)22-19(25-17)13-7-9-20-10-8-13/h1-12H,(H,21,23)/b6-4+

InChI key

QSSYRORXXFTVFI-GQCTYLIASA-N

Biochem/physiol Actions

SW157765 is a selective inhibitor of the non-canonical glucose transporter GLUT8 (SLC2A8), which exhibit potent anticancer activity on KRAS/KEAP1 mutant NSCLC cells that selectively depend on GLUT8 for glucose intake to support serine biosynthesis.
selective inhibitor of the non-canonical glucose transporter GLUT8 (SLC2A8)

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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