SML2495
MLS1082
≥98% (HPLC)
Synonym(s):
2-Cyclohexyl-10-methyl-3-phenylpyrimido[4,5-b]quinoline-4,5(3H,10H)-dione
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About This Item
Empirical Formula (Hill Notation):
C24H23N3O2
CAS Number:
Molecular Weight:
385.46
UNSPSC Code:
12352200
NACRES:
NA.77
SMILES string
O=C1C2=C(N=C(C3CCCCC3)N(C4=CC=CC=C4)C2=O)N(C)C5=CC=CC=C51
assay
≥98% (HPLC)
form
powder
color
white to gray-brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
D1 dopamine receptor PAM that binds to a different allosteric site than MLS6585 (CID 2886111)
MLS1082 is a D1 dopamine receptor positive allosteric modulator (PAM) that binds to a different allosteric site than than MLS6585 (CID 2886111). When given together, they cause an additive potentiation of dopamine potency for both cAMP accumulation and β-arrestin recruitment.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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