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SML2570

NSC 146109 hydrochloride

≥98% (HPLC)

Synonym(s):

(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride, NSC146109 hydrochloride, XI-011 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C17H16N2S · HCl
CAS Number:
59474-01-0
Molecular Weight:
316.85
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD09878281
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

S(Cc1c2c(c(c3c1cccc3)C)cccc2)\C(=N/[H])\N.Cl

InChI

1S/C17H16N2S.ClH/c1-11-12-6-2-4-8-14(12)16(10-20-17(18)19)15-9-5-3-7-13(11)15;/h2-9H,10H2,1H3,(H3,18,19);1H

InChI key

VIBMUYOXJUCEMA-UHFFFAOYSA-N

Biochem/physiol Actions

NSC146109 is a potent activator of p53 that selectively inhibits growth of transformed cells without genotoxicity. NSC146109 activates p53 by inhibition of MDMX expression.
p53 activator, inhibitor of of MDMX expression

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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