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Merck
CN

SML2575

GSHtracer

≥98% (HPLC)

Synonym(s):

2-Cyano-N,N-dimethyl-3-(2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizin-10-yl)-2-propenamide, Fluorescent real-time thiol tracer

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About This Item

Empirical Formula (Hill Notation):
C21H21N3O3
CAS Number:
1479071-34-5
Molecular Weight:
363.41
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder

Key Documents

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InChI

1S/C21H21N3O3/c1-23(2)20(25)16(12-22)11-15-10-14-9-13-5-3-7-24-8-4-6-17(18(13)24)19(14)27-21(15)26/h9-11H,3-8H2,1-2H3/b16-11+

InChI key

YCXQIYZKBAKCHQ-LFIBNONCSA-N

SMILES string

O=C1OC2=C3C4=C(CCCN4CCC3)C=C2C=C1/C=C(C#N)/C(N(C)C)=O

assay

≥98% (HPLC)

form

powder

color

faint red to very dark red

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

Biochem/physiol Actions

GSHtracer is a real-time probe monitoring of GSH (reduced glutathione) dynamics and heterogeneity.
fluorescent, real-time probe monitoring of GSH dynamics and heterogeneity

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000091961
0000091960
0000081780

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Eui Man Jeong et al.
Stem cell reports, 10(2), 600-614 (2018-01-09)
The core functions of stem cells (SCs) are critically regulated by their cellular redox status. Glutathione is the most abundant non-protein thiol functioning as an antioxidant and a redox regulator. However, an investigation into the relationship between glutathione-mediated redox capacity

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