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SML2586

(S)-C33

≥98% (HPLC)

Synonym(s):

6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, C33(S)

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About This Item

Empirical Formula (Hill Notation):
C18H20ClN5O
CAS Number:
2066488-39-7
Molecular Weight:
357.84
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD31579858
Assay:
≥98% (HPLC)
Form:
powder
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assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1C2=C(N=C(N1)N[C@H](C3=CC=C(C=C3)Cl)C)N(C4CCCC4)N=C2

Biochem/physiol Actions

(S)-C33 [C33(S)] is a potent and selective phosphodiesterase-9A (PDE9A) inhibitor that upregulates cGMP signaling. (S)-C33 protects against cardiac hypertrophy and postpones the transition to heart failure in rat models.
potent and selective phosphodiesterase-9A (PDE9A) inhibitor

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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