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SML2600

Melitracen hydrochloride

≥98% (HPLC)

Synonym(s):

Melitracen hydrochloride, 3-(10,10-dimethyl-9(10H)-anthracenylidene)-N,N-dimethyl-1-propanamine hydrochloride, U-24973A hydrochloride, 3-[10,10-Dimethyl-9(10H)-anthrylidene]-N,N-dimethylpropylamine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C21H25N · HCl
CAS Number:
10563-70-9
Molecular Weight:
327.89
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00242905
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[Cl-].[N+H](CCC=C1c2c(cccc2)C(c3c1cccc3)(C)C)(C)C

InChI

1S/C21H25N.ClH/c1-21(2)19-13-7-5-10-17(19)16(12-9-15-22(3)4)18-11-6-8-14-20(18)21;/h5-8,10-14H,9,15H2,1-4H3;1H

InChI key

RADLXCPDUXFGFF-UHFFFAOYSA-N

Biochem/physiol Actions

Melitracen is a tricyclic antidepressant (TCA) that likely exerts its in vivo efficacy similarly as imipramine and amitriptyline by inhibiting serotonin-norepinephrine reuptake.

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000071928
0000071927
0000068521

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[The thymoleptic efficacy represented by melitracen].
D Bente et al.
Arzneimittel-Forschung, 16(2), 319-321 (1966-02-01)
Relationship between the restriction of food intake and Melitracen, an antidepressant, in the rat.
K Shimamoto et al.
Acta Scholae Medicinalis Universitatis in Kioto, 40(1), 25-37 (1967-07-01)
Jin-Ying Li et al.
World journal of gastrointestinal endoscopy, 9(12), 590-593 (2018-01-02)
Jackhammer (hypercontractile) esophagus presents with dysphagia and chest pain. Current treatments are limited. We describe a 60-year-old man who presented with dysphagia, chest pain and heartburn for a period of 1 year. His workup showed Barrett's esophagus on endoscopy and
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