SML2610
Seselin
≥98% (HPLC)
Synonym(s):
2′,2′-Dimethylpyranocoumarin, 8,8-Dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-2-one, Amyrolin, Seseline
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About This Item
Empirical Formula (Hill Notation):
C14H12O3
CAS Number:
Molecular Weight:
228.24
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
[o]1c2c(ccc3c2C=CC(O3)(C)C)cc[c]1=O
InChI
1S/C14H12O3/c1-14(2)8-7-10-11(17-14)5-3-9-4-6-12(15)16-13(9)10/h3-8H,1-2H3
InChI key
QUVCQYQEIOLHFZ-UHFFFAOYSA-N
Biochem/physiol Actions
anti-inflammatory, anti-parasitic and antifungal pyrancoumarin
Seselin is an anti-inflammatory, anti-parasitic and antifungal pyrancoumarin found in anise and other plants. It appears that seselin targets Jak2 to block the proinflammatory phenotype of macrophages in models of sepsis. Seselin down-regulates levels of proinflammatory factors and activity of STAT1 and p65 in models of sepsis.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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