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SML2680

ES24

≥98% (HPLC)

Synonym(s):

2-{2-[3-(5-nitro-2-furyl)-2-propen-1-ylidene]hydrazino}-2-oxoethylbenzene

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About This Item

Empirical Formula (Hill Notation):
C15H13N3O4
Molecular Weight:
299.28
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

faint yellow to dark orange

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

Biochem/physiol Actions

ES24 is an Eeyarestatin 1 analog that blocks protein translocation in vitro and more effectively enhances Sec61-mediated Ca2+ leakage from Endoplasmic Reticulum (ER). Apparently ES24 keep Sec61 in open position allowing Ca2+ ions to move freely through the aqueous channel present. It causes cell-type-specific Ca2+-dependent cell death.
blocks protein translocation in vitro and effectively enhances Sec61-mediated Ca2+ leakage from Endoplasmic Reticulum (ER).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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