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Merck
CN

SML2695

FB23

≥98% (HPLC)

Synonym(s):

2-[[2,6-Dichloro-4-(3,5-dimethyl-4-isoxazolyl)phenyl]amino]benzoic acid

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About This Item

Empirical Formula (Hill Notation):
C18H14Cl2N2O3
CAS Number:
Molecular Weight:
377.22
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

Clc1c(c(cc(c1)c3c(n[o]c3C)C)Cl)Nc2c(cccc2)C(=O)O

InChI

1S/C18H14Cl2N2O3/c1-9-16(10(2)25-22-9)11-7-13(19)17(14(20)8-11)21-15-6-4-3-5-12(15)18(23)24/h3-8,21H,1-2H3,(H,23,24)

InChI key

VUXZATVQMFSUCM-UHFFFAOYSA-N

Biochem/physiol Actions

FB23 is a potent and selective inhibitor of N6-methyladenosine (m6A) demethylase FTO (fat mass and obesity associated protein). It moderately inhibits proliferation of NB4 and MONOMAC6 cells.
potent and selective inhibitor of N6-methyladenosine (m6A) demethylase FTO


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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