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Merck
CN

SML2712

ES9-17

≥98% (HPLC), clathrin-mediated endocytosis (CME) inhibitor, powder

Synonym(s):

5-Bromo-2-thiophenesulfonanilide, 5-Bromo-N-phenyl-2-thiophenesulfonamide

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About This Item

Empirical Formula (Hill Notation):
C10H8BrNO2S2
CAS Number:
Molecular Weight:
318.21
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Product Name

ES9-17, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O=S(NC1=CC=CC=C1)(C2=CC=C(S2)Br)=O

InChI key

AIZXCKZVUXCHAP-UHFFFAOYSA-N

Biochem/physiol Actions

ES9-17 is a potent and selective inhibitor of clathrin-mediated endocytosis (CME) that binds to N-terminal domain of clathrin heavy chain. ES9-17 inhibits uptake of different endocytic cargoes in Arabidopsis and HeLa cells.
potent and selective inhibitor of clathrin-mediated endocytosis (CME)


Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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