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SML2726

Endosidin9

≥98% (HPLC)

Synonym(s):

5-Bromo-N-(4-Nitrophenyl)-2-thiophenesulfonamide, ES9

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About This Item

Empirical Formula (Hill Notation):
C10H7BrN2O4S2
CAS Number:
693806-53-0
Molecular Weight:
363.21
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD04210333
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(Nc2ccc(cc2)[N+](=O)[O-])c1[s]c(cc1)Br

InChI

1S/C10H7BrN2O4S2/c11-9-5-6-10(18-9)19(16,17)12-7-1-3-8(4-2-7)13(14)15/h1-6,12H

InChI key

XAKPASIXPSBWRB-UHFFFAOYSA-N

Biochem/physiol Actions

potent and selective inhibitor of clathrin-mediated endocytosis (CME); mitochondrial uncoupler
Endosidin9 (ES9) is a potent inhibitor of clathrin-mediated endocytosis (CME) in Arabidopsis thaliana, HeLa cells and Drosophila neurons. It binds directly to N-terminal domain of clathrin heavy chain. Also, Endosidin9 is a mitochondrial uncoupler that displays protonophore activities leading to cytoplasm acidification.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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