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关于此项目
经验公式(希尔记法):
C10H7BrN2O4S2
化学文摘社编号:
分子量:
363.21
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
[S](=O)(=O)(Nc2ccc(cc2)[N+](=O)[O-])c1[s]c(cc1)Br
InChI
1S/C10H7BrN2O4S2/c11-9-5-6-10(18-9)19(16,17)12-7-1-3-8(4-2-7)13(14)15/h1-6,12H
InChI key
XAKPASIXPSBWRB-UHFFFAOYSA-N
Biochem/physiol Actions
potent and selective inhibitor of clathrin-mediated endocytosis (CME); mitochondrial uncoupler
Endosidin9 (ES9) is a potent inhibitor of clathrin-mediated endocytosis (CME) in Arabidopsis thaliana, HeLa cells and Drosophila neurons. It binds directly to N-terminal domain of clathrin heavy chain. Also, Endosidin9 is a mitochondrial uncoupler that displays protonophore activities leading to cytoplasm acidification.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable