SML2762
RG1534
≥98% (HPLC)
Synonym(s):
2-Amino-N-((4-((5-chloropyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)benzamide, 2-Amino-N-[[[4-[(5-chloro-2-pyrimidinyl)oxy]-3-methylphenyl]amino]carbonyl]benzamide;
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C19H16ClN5O3
CAS Number:
Molecular Weight:
397.82
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
NC1=CC=CC=C1C(NC(NC2=CC(C)=C(C=C2)OC3=NC=C(C=N3)Cl)=O)=O
InChI
1S/C19H16ClN5O3/c1-11-8-13(6-7-16(11)28-19-22-9-12(20)10-23-19)24-18(27)25-17(26)14-4-2-3-5-15(14)21/h2-10H,21H2,1H3,(H2,24,25,26,27)
InChI key
NLVSCQFSPVSAOF-UHFFFAOYSA-N
Biochem/physiol Actions
inhibitor of hTERT promoter activity that selectively targets G-hairpin stem loop of the human telomerase reverse transcriptase gene (hTERT)
RG1534 is an inhibitor of hTERT promoter activity that selectively targets G-hairpin stem loop of the human telomerase reverse transcriptase gene (hTERT) that downregulates hTERT expression. RG1534 induces mitochondrial defects, oxidative stress, DNA damage and apoptosis in cancer cell while sparing normal cells
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.