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SML2781

NV-5440

Name: NV-5440
Brand: SIGMA

≥98% (HPLC), class I glucose transporters (GLUT1) inhibitor, powder

Synonym(s):

2-[4-[5-[[4-(2-Cyanophenyl)-1-piperazinyl]methyl]-2,4-dimethylbenzoyl]-1-piperazinyl]-benzenesulfonamide

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About This Item

Empirical Formula (Hill Notation):

C₃₁H₃₆N₆O₃S

CAS Number:

2226614-88-4

Molecular Weight:

572.72

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

powder

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Properties

Product Name

NV-5440, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=C(C=C(C(C)=C1)CN2CCN(CC2)C3=C(C=CC=C3)C#N)C(N4CCN(CC4)C5=CC=CC=C5S(N)(=O)=O)=O

InChI key

BREWSTIKWAQLCH-UHFFFAOYSA-N

Description

Biochem/physiol Actions

NV-5440 is a cell penetrant, potent and selective class I glucose transporters (GLUT1) inhibitor that selectively inhibits mTORC1 pathway in vivo. NV-5440 acts as a potent inhibitor of glycolysis in cells.

cell penetrant, potent and selective GLUT1 inhibitor that selectively inhibits mTORC1 pathway in vivo

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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