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SML2796

PVHD121

≥98% (HPLC)

Synonym(s):

α-(4-Methoxyphenyl)-α-methyl-4-quinazolinemethanol

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About This Item

Empirical Formula (Hill Notation):
C17H16N2O2
CAS Number:
187336-16-9
Molecular Weight:
280.32
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC(C)(C1=NC=NC2=CC=CC=C21)C3=CC=C(C=C3)OC

InChI key

WGDUWVWCDNCAOT-UHFFFAOYSA-N

Biochem/physiol Actions

PVHD121 is potent antimitotic agent that binds to the colchicine site of tubulin. PVHD121 selectively inhibits microtubule formation at centrosomes during mitosis. It delays entry into mitosis causing long lasting mitotic arrest by activation of spindle checkpoint.
potent antimitotic agent that inhibits microtubule formation at centrosomes during mitosis

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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