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SML2843

NS3623

≥98% (HPLC)

Synonym(s):

1-(3-Trifluoromethylphenyl)-3-[2-(1H-tetrazol-5-yl)-4-bromophenyl]urea, N-[4-Bromo-2-(2H-tetrazol-5-yl)phenyl]-N′-[3-(trifluoromethyl)phenyl]urea, NS 3623

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About This Item

Empirical Formula (Hill Notation):
C15H10BrF3N6O
CAS Number:
343630-41-1
Molecular Weight:
427.18
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD22683830
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

FC(F)(F)c1cc(ccc1)NC(=O)Nc2c(cc(cc2)Br)c3[nH]nnn3

InChI

1S/C15H10BrF3N6O/c16-9-4-5-12(11(7-9)13-22-24-25-23-13)21-14(26)20-10-3-1-2-8(6-10)15(17,18)19/h1-7H,(H2,20,21,26)(H,22,23,24,25)

InChI key

JXPULDIATMTIIN-UHFFFAOYSA-N

Biochem/physiol Actions

NS3623 is a potent and selective activator of KV11.1 (hERG) and KV4.3 channels. It activates the IKr and Ito currents and exhibits antiarrhythmic activity. NS3623 may also act as a partial blocker of KV11.1 channels.
potent and selective activator of KV11.1 (hERG) and KV4.3 channels; antiarrhythmic

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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