Skip to Content
Merck
CN

Key Documents

View All Documentation

SML2854

Polmacoxib

≥98% (HPLC)

Synonym(s):

4-[3-(3-fluorophenyl)-4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl]-benzenesulfonamide, CG100649

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C18H16FNO4S
CAS Number:
301692-76-2
Molecular Weight:
361.39
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
MFCD22570958
Assay:
≥98% (HPLC)
Form:
powder
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

NS(C1=CC=C(C=C1)C(OC2(C)C)=C(C2=O)C3=CC=CC(F)=C3)(=O)=O

InChI

1S/C18H16FNO4S/c1-18(2)17(21)15(12-4-3-5-13(19)10-12)16(24-18)11-6-8-14(9-7-11)25(20,22)23/h3-10H,1-2H3,(H2,20,22,23)

InChI key

IJWPAFMIFNSIGD-UHFFFAOYSA-N

Biochem/physiol Actions

Inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrases CAI and CAII
Polmacoxib is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrases CAI and CAII. It has also been found to inhibit colorectal adenoma and tumor growth in mouse models.

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library