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SML2882

NRT-870-59

≥98% (HPLC)

Synonym(s):

7-Imino-?5-?methyl-?2-?phenyl-thieno[3,?2-?c]?pyridine-?4,?6(5H,?7H)?-?dione, 7-imino-5-methyl-2-phenylthieno[3,2-c]pyridine-4,6(5H,7H)-dione

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About This Item

Empirical Formula (Hill Notation):
C14H10N2O2S
CAS Number:
2284492-36-8
Molecular Weight:
270.31
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N=C(C(N1C)=O)C2=C(C=C(C3=CC=CC=C3)S2)C1=O

InChI

1S/C14H10N2O2S/c1-16-13(17)9-7-10(8-5-3-2-4-6-8)19-12(9)11(15)14(16)18/h2-7,15H,1H3

InChI key

IGPZTAJCUQIMOK-UHFFFAOYSA-N

Biochem/physiol Actions

NRT-870-59 is a potent and selective reversible inhibitor of PTP4A3 tyrosine phosphatase that exhibits potent cytotoxicity against human ovarian and breast cancer cells grown as spheroids. NRT-870-59 does not inhibit oncogenic dual specificity phosphatase CDC25B.
potent and selective reversible inhibitor of PTP4A3 tyrosine phosphatase

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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