SML2945
SGC-STK17B-1
≥98% (HPLC)
Synonym(s):
2-((6-(Benzo[b]thiophen-2-yl)thieno[3,2-d]pyrimidin-4-yl)thio)acetic acid, 2-(6-(Benzo[b]thiophen-2-yl)thieno[3,2-d]pyrimidin-4-ylthio)acetic acid
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About This Item
Empirical Formula (Hill Notation):
C16H10N2O2S3
CAS Number:
Molecular Weight:
358.46
UNSPSC Code:
12352200
NACRES:
NA.77
Product Name
SGC-STK17B-1, ≥98% (HPLC)
InChI key
BNYXRPMABDQJJR-UHFFFAOYSA-N
SMILES string
O=C(O)CSC1=C2C(C=C(C3=CC4=CC=CC=C4S3)S2)=NC=N1
assay
≥98% (HPLC)
form
powder
color
white to brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Quality Level
Related Categories
Biochem/physiol Actions
SGC-STK17B-1 is a cell penetrant, potent and selective inhibitor of STK17B/DRAK2 kinase.
cell penetrant, potent and selective inhibitor of STK17B/DRAK2 kinase
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Alfredo Picado et al.
Journal of medicinal chemistry, 63(23), 14626-14646 (2020-11-21)
STK17B is a member of the death-associated protein kinase family and has been genetically linked to the development of diverse diseases. However, the role of STK17B in normal and disease pathology is poorly defined. Here, we present the discovery of
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