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SML2956

Nalmefene Hydrochloride

Name: Nalmefene Hydrochloride
Brand: SIGMA

≥98% (HPLC), μ-opioid receptor agonist, powder

Synonym(s):

(5a)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylene-morphinan-3,14-diol hydrochloride, NIH 1036, Nalmefene HCl

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About This Item

Empirical Formula (Hill Notation):

C₂₁H₂₅NO₃·HCl

CAS Number:

58895-64-0

Molecular Weight:

375.89

NACRES:

NA.77

UNSPSC Code:

12352200

MDL number:

MFCD27937056

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

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Properties

Product Name

Nalmefene Hydrochloride, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

C=C1CC[C@@]2(O)[C@H]3CC4=C5[C@@]2(CCN3CC6CC6)[C@H]1OC5=C(C=C4)O.Cl

InChI

1S/C21H25NO3.ClH/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13;/h4-5,13,16,19,23-24H,1-3,6-11H2;1H/t16-,19+,20+,21-;/m1./s1

InChI key

GYWMRGWFQPSQLK-OPHZJPRHSA-N

Description

Biochem/physiol Actions

Nalmefene hydrochloride, a naltrexone analogue, is an inverse agonist at the μ-opioid receptor (MOR) and as a weak partial agonist at the κ-opioid receptor. Nalmefene hydrochloride is used as treatment for addiction.

naltrexone analogue; inverse agonist at the μ-opioid receptor (MOR) and as a weak partial agonist at the κ-opioid receptor

pictograms

GHS06,GHS09

signalword

Danger

hcodes

H301,H336,H410

pcodes

P261 - P264 - P270 - P271 - P273 - P301 + P310

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c