Key Documents

View All Documentation

SML2980

G6PDi-1

Name: G6PDi-1
Brand: SIGMA

≥98% (HPLC), G6PD inhibitor, powder

Synonym(s):

4-([5-oxo-6H,7H,8H,9H-cyclohepta[d]pyrimidin-2-yl]amino)thiophene-2-carbonitrile

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₂N₄OS

CAS Number:

2457232-14-1

Molecular Weight:

284.34

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD32899271

Assay:

≥98% (HPLC)

Form:

powder

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

G6PDi-1, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N#CC1=CC(NC2=NC=C3C(CCCCC3=N2)=O)=CS1

InChI

1S/C14H12N4OS/c15-6-10-5-9(8-20-10)17-14-16-7-11-12(18-14)3-1-2-4-13(11)19/h5,7-8H,1-4H2,(H,16,17,18)

InChI key

USWCHVCZOGGQQA-UHFFFAOYSA-N

Description

Biochem/physiol Actions

G6PDi-1 is a cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD). G6PDi-1 strongly depletes NADPH in lymphocytes. It decreases inflammatory cytokine response in macrophages, and suppresses respiratory burst in neutrophils.

cell penetrant potent and selective nonsteroidal inhibitor of glucose-6-phosphate dehydrogenase (G6PD)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library