Skip to Content
Merck
CN

SML3010

Belinostat

≥98% (HPLC)

Synonym(s):

(2E)-N-Hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide, (2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide, (E)-N-Hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide, PX 105684, PX-105684, PX105684, PXD 101, PXD-101, PXD101

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C15H14N2O4S
CAS Number:
866323-14-0
Molecular Weight:
318.35
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD08064035

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Belinostat, ≥98% (HPLC)

SMILES string

[S](=O)(=O)(Nc2ccccc2)c1cc(ccc1)\C=C\C(=O)NO

InChI

1S/C15H14N2O4S/c18-15(16-19)10-9-12-5-4-8-14(11-12)22(20,21)17-13-6-2-1-3-7-13/h1-11,17,19H,(H,16,18)/b10-9+

InChI key

NCNRHFGMJRPRSK-MDZDMXLPSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

Quality Level

100

Related Categories

Biochem/physiol Actions

Belinostat (PX105684; PXD101) is a potent, hydroxamate class pan-selective histone deacetylases (HDACs) inhibitor (IC50: class I HDAC1/2/3/8 = 41/125/30/216 nM, class IIA HDAC4/7/9 = 115/67/128 nM, class IIB HDAC6 = 82 nM) with anti-cancer efficacy in vitro and in vivo.
Potent, hydroxamate class pan-selective histone deacetylases (HDACs) inhibitor with anti-cancer efficacy in vitro and in vivo.

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Muta. 1B - Repr. 2 - STOT RE 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000269592
0000269592
0000229256
0000229256
0000182519

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service