SML3061
BSJ-04-122
>97% (HPLC)
Synonym(s):
N-(2-((5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)phenyl)acrylamide
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About This Item
Empirical Formula (Hill Notation):
C15H12ClN5O
CAS Number:
Molecular Weight:
313.74
NACRES:
NA.77
UNSPSC Code:
12352200
Quality Level
assay
>97% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
Biochem/physiol Actions
BSJ-04-122 is a cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7) that binds to Cys247 of MKK4. It potently inhibits JNK phosphorylation. BSJ-04-122 exhibits antiproliferative effects against triple-negative breast cancer cells. Also, BSJ-04-122 enhances antiproliferative activity of JNK-IN-8.
cell penetrant, potent and selective covalent inhibitor of MKK4 and MKK7 (MAP2K4/7)
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML3061-25MG | 04065267137179 |
| SML3061-5MG | 04065267137186 |