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SML3108

Voclosporin

Name: Voclosporin
Brand: SIGMA

≥95% (HPLC), Calcineurin inhibitor, film or powder

Synonym(s):

6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A, Cyclosporin A, 6-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]-, ISATX247, LX 214, R 1524

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About This Item

Empirical Formula (Hill Notation):

C₆₃H₁₁₁N₁₁O₁₂

CAS Number:

515814-01-4

Molecular Weight:

1214.62

UNSPSC Code:

12352200

NACRES:

NA.77

Assay:

≥95% (HPLC)

Form:

film or powder

Quality level:

100

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Product Name

Voclosporin, ≥95% (HPLC)

Quality Level

100

assay

≥95% (HPLC)

form

film or powder

color

white to off-white

storage temp.

−20°C

SMILES string

N1([C@H](C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C1=O)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)CC)[C@H](O)[C@@H](C\C=C\C=C)C)C

InChI

1S/C63H111N11O12/c1-25-27-28-29-41(15)53(76)52-57(80)66-44(26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27-28,35-48,50-53,76H,1,26,29-34H2,2-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b28-27+/t41-,42+,43-,44+,45+,46+,47+,48+,50+,51+,52+,53-/m1/s1

InChI key

BICRTLVBTLFLRD-PTWUADNWSA-N

Related Categories

Bioactive Small Molecules

Biochem/physiol Actions

Voclosporin is a semi-synthetic calcineurin (CN) inhibitor that exhibits potent immunosuppressive activity.

semi-synthetic calcineurin (CN) inhibitor that exhibits potent immunosuppressive activity

pictograms

GHS08

signalword

Danger

hcodes

H350,H361d

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Carc. 1B - Repr. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Global Trade Item Number

SKU	GTIN
SML3108-1MG	04065266697780
SML3108-5MG	04065266697797

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