SML3110
CRANAD-3
≥98% (HPLC)
Synonym(s):
(T-4)-[(1E,6E)-1,7-Bis[6-(diethylamino)-3-pyridinyl]-1,6-heptadiene-3,5-dionato-κO3,κO5]difluoroboron, CRANAD 3
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About This Item
Empirical Formula (Hill Notation):
C25H31BF2N4O2
CAS Number:
Molecular Weight:
468.35
UNSPSC Code:
12352202
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
gray to black
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
FB(O1)(F)O=C(/C=C/C2=CN=C(N(CC)CC)C=C2)C=C1/C=C/C3=CC=C(N(CC)CC)N=C3
Biochem/physiol Actions
CRANAD-3, a curcumin analog, is a brain barrier penetrant smart NIRF (near-infrared) probe for both soluble and insoluble Aβ (amyloid beta) species in vivo. CRANAD-3 could be used to monitor the decrease in Aβs after drug treatment in transgenic AD (APP/PS1) mice. CRANAD-3 is suitable for in vivo dually-amplify signal via chemiluminescence resonance energy transfer (DAS-CRET) with ADLumin-1 a brain blood barrier penetrant smart chemiluminescence probe for Aβs
brain barrier penetrant smart NIRF probe for both soluble and insoluble Aβ (amyloid beta) species in vivo
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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