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SML3124

Gemcabene

≥98% (HPLC)

Synonym(s):

6,6′-Oxybis(2,2-dimethylhexanoic acid), CI-1027, PD72953

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About This Item

Empirical Formula (Hill Notation):
C16H30O5
CAS Number:
183293-82-5
Molecular Weight:
302.41
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
MFCD00951832
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(O)C(CCCCOCCCCC(C(O)=O)(C)C)(C)C

InChI

1S/C16H30O5/c1-15(2,13(17)18)9-5-7-11-21-12-8-6-10-16(3,4)14(19)20/h5-12H2,1-4H3,(H,17,18)(H,19,20)

InChI key

SDMBRCRVFFHJKR-UHFFFAOYSA-N

Biochem/physiol Actions

Gemcabene is an orally available lipid-regulating compound that induces both a cholesterol and triglyceride reduction by a mechanism of action not linked to agonist or antagonist activity on the PPAR-α receptors. Gemcabene down-regulates apoC-III expression. Gemcabene is primarily metabolized (glucuronidation) by UDP-glucuronosyltransferase2B7 (UGT2B7). Thus, is often used as a UGT2B7 substrate.
orally available lipid-regulating compound that induces both a cholesterol and triglyceride reduction

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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