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SML3197

CA77.1

≥98% (HPLC)

Synonym(s):

N-(4-(6-chloroquinoxalin-2-yl)phenyl)acetamide, N-[4-(6-Chloro-2-quinoxalinyl)phenyl]-acetamide

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About This Item

Empirical Formula (Hill Notation):
C16H12ClN3O
CAS Number:
2412270-22-3
Molecular Weight:
297.74
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

Clc1cc2ncc(nc2cc1)c3ccc(cc3)NC(=O)C

InChI

1S/C16H12ClN3O/c1-10(21)19-13-5-2-11(3-6-13)16-9-18-15-8-12(17)4-7-14(15)20-16/h2-9H,1H3,(H,19,21)

InChI key

ZQXMPDVGBWOTBY-UHFFFAOYSA-N

Biochem/physiol Actions

CA77.1 is an orally available, brain penetrant, in vivo active and potent enhancer of chaperone-mediated autophagy (CMA). It improves pathology in Alzheimer′s Disease mouse models. CA77.1 activates CMA in vitro without affecting macroautophagy.
orally available, brain penetrant, in vivo active and potent enhancer of chaperone-mediated autophagy (CMA)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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