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SML3206

Ginsenoside Rg5

Name: Ginsenoside Rg5
Brand: SIGMA

≥98% (HPLC), Anti-inflammatory, powder

Synonym(s):

(3β, 12β,20E)-12-Hydroxydammara-20(22),24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):

C₄₂H₇₀O₁₂

CAS Number:

186763-78-0

Molecular Weight:

767.00

UNSPSC Code:

12352107

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

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Product Name

Ginsenoside Rg5, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)O[C@@H]3C([C@H]4[C@@]([C@@H]5[C@]([C@]6([C@H]([C@@H](C5)O)[C@H](CC6)\C(=C\CC=C(C)C)\C)C)(CC4)C)(CC3)C)(C)C

InChI

1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10-11,23-38,43-50H,9,12-20H2,1-8H3/b22-11+/t23-,24-,25-,26-,27+,28-,2

InChI key

NJUXRKMKOFXMRX-RNCAKNGISA-N

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Related Categories

Bioactive Small Molecule Inhibitors

Bioactive Small Molecules

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

0000463942

0000413800

0000369198

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Specific activation of insulin-like growth factor-1 receptor by ginsenoside Rg5 promotes angiogenesis and vasorelaxation.

Young-Lai Cho et al.

The Journal of biological chemistry, 290(1), 467-477 (2014-11-14)

Ginsenoside Rg5 is a compound newly synthesized during the steaming process of ginseng; however, its biological activity has not been elucidated with regard to endothelial function. We found that Rg5 stimulated in vitro angiogenesis of human endothelial cells, consistent with

Hypoglycemic Effect of Ginsenoside Rg5 Mediated Partly by Modulating Gut Microbiota Dysbiosis in Diabetic db/db Mice.

Yange Wei et al.

Journal of agricultural and food chemistry, 68(18), 5107-5117 (2020-04-21)

In this study, we aimed to investigate the influence of ginsenoside Rg5 (Rg5) on gut microbiota in diabetic db/db mice. Our data indicated that Rg5 not only improved the symptoms of hyperglycemia, repaired intestinal barrier function, and relieved metabolic endotoxemia-related

Anti-inflammatory effect of ginsenoside Rg5 in lipopolysaccharide-stimulated BV2 microglial cells.

Yu Young Lee et al.

International journal of molecular sciences, 14(5), 9820-9833 (2013-05-24)

Microglia are resident immune cells in the central nervous system. They play a role in normal brain development and neuronal recovery. However, overactivation of microglia causes neuronal death, which is associated with neurodegenerative diseases, such as Parkinson's disease and Alzheimer's

Global Trade Item Number

SKU	GTIN
SML3206-5MG	04065267366494

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