SML3208
CPYPP
≥98% (HPLC)
Synonym(s):
4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione
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About This Item
Empirical Formula (Hill Notation):
C18H13ClN2O2
CAS Number:
Molecular Weight:
324.76
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
SMILES string
Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3
InChI
1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)
InChI key
VVZJFICTTKPNCK-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
orange to dark red
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
Quality Level
Related Categories
Biochem/physiol Actions
CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.
cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain
Storage Class
11 - Combustible Solids
wgk
WGK 3
Regulatory Information
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