SML3211
Mogrol
≥98% (HPLC)
别名:
Mogrol, (3β,9β,10α,11α,24R)-9-Methyl-19-norlanost-5-ene-3,11,24,25-tetrol
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关于此项目
经验公式（希尔记法）:
C30H52O4
化学文摘社编号:
分子量:
476.73
UNSPSC Code:
12352107
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
O[C@H]1[C@@]2([C@H]([C@]4([C@@]([C@H](CC4)[C@@H](CC[C@@H](O)C(O)(C)C)C)(C1)C)C)CC=C3[C@H]2CC[C@@H](C3(C)C)O)C
InChI
1S/C30H52O4/c1-18(9-13-24(32)27(4,5)34)19-15-16-28(6)22-12-10-20-21(11-14-23(31)26(20,2)3)30(22,8)25(33)17-29(19,28)7/h10,18-19,21-25,31-34H,9,11-17H2,1-8H3/t18-,19-,21-,22+,23+,24-,25-,28+,29-,30+/m1/s1
InChI key
JLYBBRAAICDTIS-AYEHCKLZSA-N
Biochem/physiol Actions
Mogrol is an aglycone of mogrosides from Siraitia grosvenorii that exhibits neuroprotective and anticancer activities. It induces apoptosis in K562 leukemia cells through suppression of ERK1/2 and STAT3 pathways. Mogrol appears to ameliorate the memory impairment caused by Aβ1-42 in mice. Mogrol increases AMPK activity in hepatocytes and suppresses adipocyte differentiation in 3T3-L1 cells.
aglycone of mogrosides from Siraitia grosvenorii that exhibits neuroprotective and anticancer activities; suppresses adipocyte differentiation
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable