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SML3227

KI-ARv-03

≥98% (HPLC)

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关于此项目

经验公式（希尔记法）:
C14H21N5
化学文摘社编号:
2416873-72-6
分子量:
259.35
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
(Powder or Lyophilized powder or film or oil)
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Quality Segment

100

assay

≥98% (HPLC)

form

(Powder or Lyophilized powder or film or oil)

color

colorless to brown-yellow

storage temp.

2-8°C

SMILES string

CCCC1=NC2=CC=NN2C(N[C@H]3C[C@@H](CC3)N)=C1

Biochem/physiol Actions

KI-ARv-03 is a cell penetrant, potent and selective inhibitor of CDK9 that that reduces AR-driven transcription and proliferation in prostate cancer cells. KI-ARv-03 modulates AR and AR-V7-dependent transcription in 22Rv1 cells. It exhibits potent anti-tumor activity in castration-resistant prostate cancer (CRPC) models.
Orally available, potent, ultraselective CDK9 inhibitor that exhibits potent anti-tumor activity in castration-resistant prostate cancer (CRPC) models

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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