SML3251
GRL-1720
≥98% (HPLC)
Synonym(s):
1H-Indole-4-carboxylic acid 5-chloro-3-pyridinyl ester, 5-Chloro-3-pyridinyl 1H-indole-4-carboxylate, GRL 0496, GRL-0496, GRL0496
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About This Item
Empirical Formula (Hill Notation):
C14H9ClN2O2
CAS Number:
Molecular Weight:
272.69
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
eCl@ss:
32160701
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: ≥2 mg/mL, clear
storage temp.
2-8°C
SMILES string
ClC1=CN=CC(OC(C2=CC=CC3=C2C=CN3)=O)=C1
InChI key
BOSZJNSICHFHMA-UHFFFAOYSA-N
Biochem/physiol Actions
GRL-1720 is an irreversible, covalent inhibitor of SARS-CoV-2 Mpro that blocks virus replication. GRL-1720 protects VeroE6 cells form SARS-CoV-2WK-521 infection. It shows no significant cytotoxicity to several cell lines.
Irreversible, covalent inhibitor of SARS-CoV-2 Mpro that blocks virus replication
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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